Prevalence of Macrolide-Lincosamide-Streptogramin B (MLSB) Resistance in S. aureus Isolated from Patients in Tehran, Iran

Prevalence of Macrolide-Lincosamide-Streptogramin B (MLSB) Resistance in Staphybcoccus aureus Isolated from Patients in Tehran, Iran

Background and Objectives: Staphylococcus aureus is an important cause of nosocomial and community-acquired infections in every region of the world. Clindamycin is one of the alternative agents used to treat S. aureus infections and accurate identification of clindamycin resistance is important to prevent therapeutic failure. Unfortunately, inducible clindamycin resistance is not detected by st...

prevalence of macrolide-lincosamide-streptogramin b (mlsb) resistance in s. aureus isolated from patients in tehran, iran

background and objectives: staphylococcus aureus is an important cause of nosocomial and community-acquired infections in every region of the world. clindamycin is one of the alternative agents used to treat s. aureus infections and accurate identification of clindamycin resistance is important to prevent therapeutic failure. unfortunately, inducible clindamycin resistance is not detected by st...

Phenotypic and genotypic study of macrolide, lincosamide and streptogramin B (MLSB) resistance in clinical isolates of Staphylococcus aureus in Tehran, Iran

BACKGROUND Resistance to antimicrobial agents among Staphylococcus aureus is an increasing problem. Two common genes responsible for resistance to macrolide, lincosamide and streptogramin B (MLSB) antibiotics are the ermA and ermC genes. Three resistance phenotypes have been detected to these antibiotics: strains containing cMLSB (constitutive MLSB) and iMLSB (inducible MLSB), which are resista...

Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinants.

Heterogeneity of macrolide-lincosamide-streptogramin B resistance phenotypes in enterococci.

We determined the macrolide resistance phenotypes of 241 clinical isolates of erythromycin-resistant enterococci (MICs, > or = 1 microg/ml), including 147 Enterococcus faecalis strains and 94 Enterococcus faecium strains, collected from a hospital in Seoul, Korea, between 1999 and 2000. By the erythromycin (40 micro g)-josamycin (100 microg) double-disk test, 93 strains were assigned to the con...

Macrolide-lincosamide-streptogramin resistance patterns in Clostridium perfringens from animals.

Different patterns of resistance against commonly used macrolide, lincosamide, and streptogramin antibiotics were found in Clostridium perfringens of animal origin. The patterns were designated as (i) macrolide-lincosamide-streptogramin group B generalized resistance, (ii) macrolide-lincosamide generalized resistance, (iii) macrolide-lincosamide inducible resistance, and (iv) macrolide-lincosam...